Joe Rogan Experience #1701 — Dr. Rhonda Patrick Transcript

Transcript

0:00 the Joe Rogan experience burning fatty acids and making keto bodies and using them as energy, matston have you heard of him no he's like legendary i mean he's probably one of the you'll die so um so he's talking about like one of the main things that happens is this metabolic switch, So it actually requires energy to use glucose as energy, to make energy from glucose requires

3:29 So it takes energy to do that. And then pyruvate has to be transported into the mitochondria through a like active transport mechanism. So that's kind of like what most people are thinking about is this sort of metabolic switch that happens. always in this like fat storage state instead of a fat burning state, right? And so, because most people are eating three meals a day and plus snacks, you just,

5:59 that beta-hydroxybutyrate activates many different genes, one of them including it's a hypothesis, but, you know, it seems like something that people could test and seems kind of, you know, it makes sense, right? Dr. Dom D'Agostino has talked about this. we're like engaged, intellectually engaged. And so glutamate's being ketosis, like, I think, you know, you want to be somewhere between like 0.9 and like 1.2. I mean,

9:26 the beginning, like, if your body like me, so I've always, you know, for the most part, my diet has It's just a little like it has been a huge challenge. And that kicked me down to like 0.4. Your body has a way. Or you can make it from glycerol, which is like the background of a triglyceride. all these recipes like i'm going online i'm trying to do keto recipes and all this and it's like

13:12 I'm not an expert. honestly. Is there any benefit to using exogenous ketones? than the salts. Salts are not very effective at all. It'll be a liquid. So the liquid is more effective than the salt. well um they'll raise you up like if you do if you for example if you drink like the whole serving The exogenous ketone esters. Two hours max. So I have, I used to kind of use them that way.

16:32 So and I noticed that like several times. I tried the mental stuff but so um getting someone something or grabbing like a, you know, some spoon or whatever. And then she has orthostatic with like Parkinson's disease in animal models, Alzheimer's disease, like that's, you know, It tastes like shit. So, you know, it's kind of like. can help with migraines as well. I mean, they're like not like the best done, you know, I mean,

20:14 and coca-cola yeah she would say it fixes her migraines yeah it does like does it according is impaired glucose, like brain use of glucose. Like people, We've known this for, like, over a year. doing the lowest hanging fruit in terms of what's like the least amount of work bacon bacon They're giving me a lot of stuff like potassium, but the magnesium, which I'm now supplementing

23:21 eating more of it you're eating more you don't like if you're eating spinach salad you would stop you're like oh this is a big old bowl like too much right but you eat that And you're eating meat pretty much every day? And they have a keto place? It's called Keto Kitchen. Oh, but it like a keto place. I ordered it from my postmates to my hotel. They have a keto place?

24:42 Yeah, so the cauliflower hash. that. Great question. Maybe Dom D'Agostino knows, maybe I'll figure it out. I don't know. But, um, And that's, you know, she's like increasing her carb intake basically so but still you know for someone like me it's like like even like you But I'm finally like I finally got the motivation once it was like very noticeable mental.

27:33 been working out more because you can actually kick yourself into ketosis by doing that because glucogenic amino acids are like some of the branch chain amino acids that you amino acids up into muscle and some of those glucogenic amino acids are like they didn't do anything what's wrong with this lady She's got bacon and avocados in her bag. you got to eat and when you can switch over to more of that but like i'm learning about this and i'm going holy shit like i thought i could just eat some

30:14 And they're in olive oil. asking me questions like what's your diet like we go over that he goes what is there any uh do you contain a lot of heavy metals apparently oh my gosh yeah pollution oh no oh no i mean this is They're dirty little buggers. while i was breastfeeding either because i don't want to transfer that to breast milk but there are warnings where people say you

32:39 Oh, I was eating sardines, but different thing. People that eat a lot of sushi, they can get mercury issues, right? fish yeah because they eat they eat like smaller fish and it accumulates. Yeah, so it's accumulating in their fat. but is to take like a fish oil supplement of course you can't it's not sustainable like if but is it available to you right now?

34:55 So like I get so confused when people want everything to be sustainable to the whole No, it is not. But like there have, so I've looked at some studies. Yeah. like a much higher level of some of those things. just you can't eat as much like you you get full quicker. Like your body just gets satisfied by it quicker. Grass-fed, grass-finished beef is much darker and has much less fat,

38:14 the ones that are growing, like having the cows all packed in and they're, you know, I don't know. and he is a young, healthy, black belt in jiu-jitsu. Yeah, MRSA will take anyone down. you can't give your animal antibiotics unless it's prescribed by a veterinarian and they have Yeah. I mean, you know, so imagine the amount of antibiotics to like just nationwide in the United States alone.

41:23 And do we know why it makes them big? I don't remember. probably has to do something with that but like i just don't remember the exact it's crazy though It's a scary thing. And I had never tested the actual abscess to know if it was actually MRSA. It just wants, you know, I think it also depends a lot on like your immune system, Anyways, so then I got another abscess in a different region.

44:25 like, what the hell? Like, this isn't working. And I started looking into the literature on, was showing to have like an effect particularly on MRSA and so I was putting tea tree oil and Yeah. I would feel any sort of sick or anything like that. But the oil is highly concentrated. Yeah, it was garlic oil that I was doing at the time. I mean, I think my memory was something like two days.

47:42 and I got pretty sketched out by it because I've had staph in the past, but I killed it with topical spray. There's Defense Soap, I managed to kill it, but I was nervous um it's been a while no no i don't get the uni part but it's like it's like down on my eyelid root more and they get i don't know whatever i got fucked up from it i got folliculitis and it

50:11 Oh, boy. Yeah. Right, right. it's usually from using steroids because they use steroids, I thought it would just be fluid. to take out this gynomastica. Because people need to see it. Yeah. see that stuff in the right hand corner I mean these are huge things hormonal imbalance, just a natural irregularity. They are boobs. like aromatherapy, you you know you breathe it in and it's

54:41 Damn, you're getting all the benefits. If you're sick with a viral infection and your body gets a fever, your body is trying range right partly yeah i mean there's there's multiple mechanisms that also activates heat coming out of Dr. Jari Laukkonen's lab in Finland. And this was after like correcting for all sorts of like other lung diseases and other health factors and exercise and all that stuff,

57:52 So in other words, you know, like you as you age, you become more susceptible to things like, you know, cancer, Alzheimer's disease, heart disease, respiratory problems, all that stuff. And, you know, it's a lot easier for people, at least I've noticed with my mom, you know, who views it as like a spa treatment. is like a no-brainer yeah a no-brainer i mean granted there are some contraindications like

1:00:10 arrhythmias, there could be a very mild contraindication with arrhythmias. And so the Like, these things have been compared head to head. there's a lot of environmental factors at play, you know, like drinking Cokes, like refined sugar, some, it's, it's called the heckle device. It's like this crazy thing that it's kind of infrared They're going to feel better.

1:02:57 One session. And she sort of carried on the torch. with her head out and they're in there for a long time and um they're measuring their rectal temperature and making sure they get up to like 101 and it's like a silicone probe it's really and use it as a potential clinical treatment for depression. So now the study that she's going to be starting any day, which I'm collaborating with her on, is she's

1:05:41 And there's been studies showing hot baths increase brain drive neurotrophic factor, BDNF. response in some cases, like IL-10 and things that are anti-inflammatory. Anyways, he found How much body temperature, what do you think your body temperature is getting to if you're at like what I do, which is like 185 degrees for 20, 25 minutes? people don't trust you with a rectal thermometer. They're like, hey. Yeah, I definitely agree with that.

1:08:09 I've done it at Rick Rubin's. yeah i have an ice bath i have an ice bath right next to the sauna i do it every day what do you which is really odd were using the pool because the pool was cold right it was like you know not 50 degrees yeah Like, you know, I was getting my heat stress on, right? like assuring me it's okay. It's okay. And, um, and this lasted a couple of minutes, like a couple of minutes.

1:10:39 I don't know if I had gotten cold water in my ear. A lot of them have to get, they have to get operations on it. Over time, this can eventually cause a partial or complete blockage of the ear canal. I got a little thing I bought on Amazon. hurts like I can't sleep with them because it hurts I wore ear guards all throughout my years and open it it's very different between what it sounds like like this

1:13:48 But they can't hear anyway, so then, you know. it was weird so you hear music like clearly that's it just vibrates on your bones instead and then they cut out all the calcified blood, Yeah, that's what it looks like. Randy Couture, you don't hear much yeah look at that one uh okay yeah is there balance off or anything like that Because it's amazing how much fluid comes out of a cauliflower ear.

1:16:55 And once you get it in there, you really should go low. Good thing you were wearing those ear protectors. your head. Yeah. and I was at the three-minute mark. where like everything feels like shaky and back like 49 degrees Fahrenheit and he gets in for like 12 minutes i mean he's just in there like he loves it he does it like first thing in the regulates that is, you know, norepinephrine, which is a hormone and also a neurotransmitter,

1:20:28 You know, like they have gone over to Finland and done it. hot in there and a minute cools me off and I get a little weirded out but not crazy but when I did But then coming out of the sauna, it's super shaky. Well, mine was a little weird too. right now, like if I just sunk in there right now, my visual field would be fine. Yeah. But So I'm doing 25 minutes and I'm at 190 degrees sometimes.

1:23:51 blood pressure goes down. And this is like one of the reasons why it's so cardioprotective among myself i'm like hey don't die stupid i know it's a dumb way to die yeah totally yeah i was like And it feels really relaxing. Yeah, reasonable. He really is into it, like big time, like just doing it alone. to a lot of books on tape in the sauna, but now primarily I do just nothing.

1:26:41 done that since I listen to sets like comedy sets that I've done because it'll help me tune in for the next one. but you know when I go on a podcast like when I you know this is my 10th time on this podcast And the way you communicate certain things I suggest earphones. on because then your volume is the exact same volume as mine. So if you're talking

1:29:26 So if I have two guests and they don't have headphones on, it's just madness. You have to because you have to realize how bad this sounds right totally yeah yeah well so what else have you on the sauna and cardiovascular health, a lot of that. But this goes into the all cause mortality, body of literature, I think. And so I'm just pretty excited about that. It's also open access to public, so it's not paywalled. So people can access this article. They can also go to my website where I have the topic page on it gist of it it's it's not necessarily something

1:32:17 I really think that there's got to be a connection with the sauna, you have even more improvement in your cardiorespiratory fitness than if you But with the sauna, like it's really good when you're not doing that work, you know, needs to be worked out but it seems as though like doing an ice bath immediately after strength It's a growth factor that you make in your muscle in response to exercise.

1:35:39 The sauna doesn't, the sauna actually, like exercise, it actually increases inflammation. I don't know. has already been activated because you've already gone through it, who never had any interest in using sauna before Plus, I also think there's lots of effects on mood. Your red blood cells, you accumulate it in the cell membrane and, cell membrane and your red blood cells take 28 days before they turn over. And so, whereas if you were to have

1:39:32 omega-3 index. So like there's one study that he did was published last April. So a few months ago, I don't know. I was like, they're less likely to get in some kind of crazy accident that causes them to die. something. This is measured in your blood. This is a long-term marker. This is real data, right? Yeah. but you have to convert it into epa and dha and it's like that conversion's not very good it

1:43:02 The fish eat that, and it concentrates in their fat and stuff. That would be the way to go. But a lot of the therapeutic studies, like they've done randomized controlled trials showing that you can drop cardiovascular death by like 25% if you give people with a various range of heart diseases four grams of a purified form of EPA. It's purified EPA.

1:44:44 I've never i've It tastes nasty. their website and look at each product sheet. And you have to kind of do it often because they Don't know how to do it because it's kind of complicated so hopefully that'll help people find some brands that have again you have to like this is you know you never I think he might in Norway, maybe. them. There was some like, like you know evidence conflicting in the literature

1:48:21 Well, cod liver oil is, you know, the's high, the micronutrient it's most high taking it if you want to get your vitamin a and vitamin d through cod liver oil you could i don't I'd be ODing on the vitamin A. Sometimes in the summer I can go with less, but it really depends on the season. Like you're not. So Bill Harris, Dr. Bill Harris, he just published a pilot study on the omega-3 index and COVID death.

1:51:57 vaccines are probably the best way to prevent yourself from both getting and having a severe they can't bind to the ACE2 receptor. So they can't, you can't even latch on. And there was a major source of driving the aging process. And there's been studies that have looked at, Like none of the other things predicted each, you know, going to the next stage.

1:54:51 grams of fish oil a day and i eat sardines and i you know eat salmon so you know it's kind of He flew out for a podcast like last week. And, like, doing, like, metabolic ward studies. So you'd think if anyone knows about negative effects i don't remember like we i the podcast is coming out in a couple of weeks okay you know if you The omega-3s do affect your leukotrienes and prostaglandins and things that do affect, you know, like platelet aggregation and stuff.

1:58:21 this is super like preliminary. It's not really known. people have been studying the human body that there's still so much speculation as to what very high. And the percentage of people that did they're probably like, how much time do they spend on nutrition in medical school? Or get a doctor that concentrates on that and go to him when you're dealing with like

2:01:06 And it's like, it's constant and it never ends. to see if a treatment is working, right? Or if X comes out of, you know, or if Y comes out of X or you know, beta carotene or, you know, something. And you realize, oh, they eat a lot more vegetables we looked at this X point, end point, X, like cancer incidents. We didn't measure anything after. And it's like,

2:03:10 They're not measuring anything. Like drugs, people don't have that to start with. I can't even stay on top of it. And now that I'm a mother, it's even more difficult, you know, but, you know, there's all my notes and I have flash you can know that amount, it helps. essential fatty acids and your vitamins and your nutrients and your minerals and Right.

2:05:39 Like there's a question and I'm like diving into it. all the same shit that got them in the mess in the first place, I did 60 sessions of 90 minutes over 90 days outlier that's for sure i think i think there's some you know thoughts that it like helps increase Right. And now, I think now more ever, like being healthy is even more important. I don't think they believe it or they might just, you know, it's just too much work.

2:10:08 It's like you're building a mountain with a layer of paint at a time. it's not like, you know, something like a vaccine would do, but it's, it's definitely plays a role but I think the eight really are that, you know, a more virulent strain or variant. And then there's one more that, oh, alternatives to vaccines exist right now that are just as good. And I think that there's a few of those that are really,

2:12:23 Well, of course. I mean- Do you know anyone that's had are harmful to anyone? Well, of course. It's a big world out there. Every 30 seconds. And there's speculation, right? And even people are getting myocarditis like hundredfold times more than vaccines like the myocarditis link from thefold times more than vaccines. Like the, the myocarditis link

2:15:59 And how do you recover from that? It can lead to that, yeah. infected with? Or do you think it's their immune system that fights it off? Like, then there's the argument well i'm healthy i don't have comorbidities, right? I mean, so what should I do? Like, should I, you know, get vaccinated or should I be exposed to the virus? And I think there's a lot of evidence and there's multiple lines of evidence. One, you know, there are people with mild symptoms that are getting post-acute COVID syndrome.

2:18:36 You know, there was a study published in The Lancet like last year showing there was a sevenfold increase in stroke incidents in people under 50 in the Without the spike protein. this is only five percent covid was the only cause and then so for only five percent of the that have negative effects, like that have had strokes or that have had thrombosis or myocarditis

2:20:49 athletes, you know, and people are- Has it been shown in large numbers? Like the athletes- if there's like something that's life-threatening, that myocarditis is caused by the vaccine? Is there encouragement or discouragement to submit to VAERS? Because according to this, what we pulled up, it's 5% that are dying just of the COVID. where right before the pandemic started,

2:23:22 the same cohort of people back in for a brain scan. How many people did they study with this? Did they have comorbidities? I don't know if any of that data was in it. i do know most of them had some kind of weird taste issue like or smell thing for like weeks they were asymptomatic and they were younger people. So it's like, you'd think, well, if they were had four comorbidities and they had COVID, they'd know it, right?

2:26:56 So this is important because the spike protein from the SARS-CoV-2 virus is a different spike protein than what's in the vaccine. It's a different protein. spike protein is harmful in those studies. And it's binding to the ACE2 receptor. And once it has a half-life of a few hours, a few hours, long enough to protect the mRNA from degrading. of the Pfizer-BioNTech vaccine. So humans, we get 30 micrograms per injection. They gave the rat 50.

2:31:03 immediately when something foreign like this lipid nanoparticle, they chew it up into pieces. the animal equivalent dose, which was two micrograms. And there was a little bit found But it turns out like this test, the Samoa, is really good for looking at like IgG antibodies. that. Like that, to me, is like, you can't make any claim from that. There's no way.

2:33:40 It's different. if you're looking at clinical trials in terms of, you know, preventing SARS-CoV-2 infection causing blood clots in people, even people that are healthy, you know, like people that are, Well, I mean, in theory, yeah, it is. He's the one that basically did this two-point mutation and kept the spike protein in the pre-fusion complex. And this was work that he had done previously with RSV,

2:36:27 and toddlers, but 80% of the infants and toddlers that got the vaccine and then were exposed to the, vaccine is supposed to be protecting you from. And for a long time, and I know I think Jason But, you know, the vaccines that we're using in the United States are. That misinformation, it's misinformation. I think I was reading something today about that, that the majority of the people that are hospitalized in Israel were vaccinated. And they're attributing that to the higher rate of vaccinations in Israel. And that the idea that these vaccines have a waning life of effectiveness, so that after,

2:39:44 words, people with lower neutralizing antibodies were more likely to get this breakthrough infection. And it predicted the breakthrough infection. In other words, people with lower unvaccinated. And it was looking at, you know, effectivity of the vaccine. So in other words, Yeah. I mean, some places aren't doing that, but you'd have to do a PCR test.

2:41:46 actually much better. It dropped down to like 77% effective. But the side effects of the Moderna were a little stronger as well, right? Because the Moderna conferred more of the spike protein and Like the vaccines are protecting people from getting this virus because there's still some effectiveness of them. But there's lots of studies showing the people in the hospitals are older, of course, the ones getting the breakthrough infections.

2:43:30 Okay, so it's not preventing. they saw that while the initial levels of It's a real-time study that's going on in the UK where they get all this data real-time. these are still happening to people who are vaccinated who get COVID, right? It's a reason on the individual level to. and never, you know, it's eventually going to. stuff that I always do in terms of my protocol, like with the sauna and all the other stuff that

2:47:26 It's either Quest or LabCorp. Here's another question. Is that the road that we're getting on? the four comorbidities or two or whatever it is, any comorbidities probably, those people are, for like four months right like and there's phase one phase two phase three right but initially the been fully vaccinated, they're pretty equal in terms of as likely to get a breakthrough infection

2:50:51 A good friend of mine who's an elite athlete got infected with COVID. It was nothing. He All the other friends that I've had that were vaccinated after they had COVID had no problems. We know about the blood clotting from the adenoviral vector vaccines, including Johnson & Johnson. ivermectin, but it's not, there's not something that there's like real rock hard data that you

2:53:30 And what I see and I mostly see that a lot of people doing this in on websites, they're like aggregating all this data and putting it together. okay? And then you have the control groups vary considerably. They're getting, you know, When you get negative, you have people looking at hospitalizations. sizes in such case that the incidence of something is going to be so small because the sample

2:55:51 There is a huge overstatement for whatever reason. it is doing harm and i had a knee- jerk reaction at first. It was like, oh, being hospitalized by vaccine. There's certainly, I don't even know if there's any evidence on So these treatments, yeah. these these you know grandiose statements and and to be honest the prophylactic data like there was So I do think, you know, it is my opinion that like, I've known people, not known them

2:59:31 icu with the husband no with covid they got covid and then it was like bad and they were taking And yeah, so it's like, what effect is having it once a week have for multiple weeks i if the ICU is full. I've got a lot of thoughts on it. vaccinated while you're pregnant? I think the data so far has suggested I'm, someone that's like, So, yeah. It's on Apple Podcasts.

3:02:47 People want to dive deeper. Always a pleasure.