JRE Database

Brian Simpson

Guest: Brian Simpson

Date: 2026-04-29 | Duration: 2h 32m

Category: Health & Medicine, Nature & Outdoors

Episode Overview

Joe Rogan hosts Brian Simpson for a wide-ranging discussion on personal anecdotes, technological advancements, and the mysteries of the universe. The conversation begins with Joe's recent experiences with red light therapy improving his vision, leading Simpson to recount his own humorous and harrowing heart attack experience in Atlanta, including joking with an unamused surgeon and reflecting on the nature of medical professionals. They also delve into their mutual love for pets, with Simpson detailing his cat's fiercely independent personality and Joe sharing a story about his dog, Marshall, eating rocks. The discussion then shifts to the fascinating world of technology and nature. Simpson shares his passion for advanced video gaming setups and streaming, while Joe introduces the concept of AI-powered information retrieval. They explore the peculiar effects of catnip on felines and the rapid domestication of foxes in Russian experiments. The conversation takes a turn towards the inexplicable with discussions about the expansion of the universe, newly discovered black holes, and mysterious megastructures found beneath Egyptian pyramids. They conclude with a bizarre story about a "super syphilis" outbreak in Michigan, illustrating the unpredictable nature of both human behavior and biological threats.

About Brian Simpson

Brian Simpson is a content creator and gaming enthusiast known for his advanced video gaming setups and streaming work. During his appearance on the Joe Rogan Experience, he demonstrated a wide-ranging curiosity about topics from personal health experiences to cutting-edge technology and cosmology. Simpson is particularly notable for his ability to engage in wide-ranging conversations that blend humor with substantive discussions about everything from gaming culture to the mysteries of the universe.

Key Moments

Transcript Excerpt

[00:00:01] Joe Rogan podcast, checking out. The Joe Rogan Experience. Train by day, Joe Rogan podcast by night, all day. Do you gotta get new glasses? No, I just have a different pair for different stuff. Did they get stronger? No. No? [00:00:19] I just have a... Did you always have glasses? Like, do you have an eyeball issue? Yeah, I got a stigmatism. Okay. But I got one for driving and one for my computer. I used to have to use reading glasses. Oh, yeah? [00:00:33] Then I started using red light. Red light therapy, and I think that, the first thing I started doing is taking, this company Pure Encapsulation has this, it's called macular support. It's like a combination of nutrients that help your eyeballs. Oh. I don't know how. But I explained it to Huberman, and he read it off to me, and he's like, this makes sense. But then the big one was red light. I started using red light therapy. [00:01:18] They definitely use dark light in restaurants. I don't, I mean, young people can still read it. Like, I've gone to restaurants with my kids and they can read in the dark. I'm like, you can read that? I can't read it. But, like, small print, like on my phone. own, like reading an email, I didn't used to be able to read it, and now I can read it perfectly. Oh, see, now, I'm hitting that age now where I've got to start. [00:01:40] Switching. Switching glasses. Different. Yeah. Here we go. Here we go. Listen, dude, I'm just happy you're alive. Oh, yeah, yeah, yeah. [00:01:59] In Atlanta. Yeah. Out of nowhere. Well, was it really out of nowhere? Not really. You know, like, because that's not like you were a marathon runner. Right, right, exactly. But I was sitting there, you know, honestly, I was sitting there thinking, because I remember the doctor, because, you know, we really are, like, we've set ourselves up. [00:02:26] We kind of deal with trauma and an anatomy. I mean, you can argue about whether it's, whether it's healthy or not. But I'll first go to his humor. Ri...

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Frequently asked about this episode

Who was the guest on Joe Rogan Experience #2491?

Brian Simpson was the guest on JRE #2491. This page includes the episode overview, topics discussed, and related resources.

What topics were discussed on JRE #2491?

On Joe Rogan Experience #2491 with Brian Simpson, topics include Joe discusses red light therapy for eyesight, Brian recounts joking during his heart attack procedure, Brian's reflex to protect his groin during stent placement, and Doctors vs. Nurses' sense of humor.

Where can I read the transcript for JRE #2491?

The full searchable transcript for Joe Rogan Experience #2491 with Brian Simpson is available on this page, along with key topics and timestamps.